A number of indigenous populations have resided at high-altitude for generations, resulting in various phenotypical adaptations promoting successful high-altitude adaptation. While many of these adaptations have been investigated in adults, little is known regarding how children residing at high-altitudes adapt, particularly with regards to the cerebrovasculature. Under hypoxic environments, compensatory changes in cerebral blood flow (CBF) are necessary to couple oxygen delivery to metabolic demand in the face of reduced oxygen availability.
View Article and Find Full Text PDFBackground: Breast cancer ranks as the second most prevalent malignancy among women in Nepal. This cancer has a high likelihood of cure, if detected early. Therefore, it is imperative to emphasize awareness and screening for breast cancer in Nepal.
View Article and Find Full Text PDFBackground: Stroke is a potential complication of Transcatheter Aortic Valve Replacement (TAVR). Recent trials evaluating Cerebral Embolic Protection Systems (CEPS) to reduce the incidence of stroke after TAVR have been conflicting.
Methods: Multiple databases were searched for studies comparing TAVR with or without CEPS and that reported on the primary outcome of periprocedural stroke.
This study aimed to assess the relationship between menstruation-related attributes and mental distress in adolescent girls. A cross-sectional study was conducted in Rangeli Municipality, Nepal, among 270 adolescent girls. Data were collected using a self-administered questionnaire.
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