On certain morphological aspects of regenerative significance in nodular adenomatous thyroid.

The histologic study of 59 nodular adenomatous thyroids showed the existence of new-growth follicles originating in the preexistent ones. These changes, correlated with various circulatory disturbances, necrosis or chronic inflammation, their striking parallelism with the morphological aspects encountered in the course of thyroid histogenesis, strongly suggest their regenerative significance. The frequency and importance of such changes in the morphogenesis of adenomatous nodular thyroid are also emphasized.

Morphological significance of associated epithelial cords and ductlike structures in certain tumors of the pancreatic islets.

The association of epithelial cord cells and ductlike structures in 2 cases of pancreatic islet tumors is presented. The first case was characterized by multiple pancreatic nodes of beta cell insulinoma in a 35-year-old woman. The second case was a Zollinger-Ellison syndrome in a 10-year-old male child with perforated duodenal ulcer due to an islet cell tumor of an aberrant pancreas in the omentrum.

On skeletal muscle pathology in trichinosis.

A study was carried out on the pathology of trichinosis in human muscle biopsy sample and comparatively in experimental trichinosis in the rat, by current microscopic techniques and Troitsky's method of block silver impregnation of the nerve endings. Stress is laid upon the incipient changes in the parasitized muscle fibers, the sarcolemmic origin of the parasite capsule, the myogenic nature of certain periparasitary but intracapsular clear cells of precocious appearance and other associated, non-specific lesions, such as common myositis changes or giant myogenic foreign-body cells. The intimate relationships between parasitized muscle fibres, cellular interstitial reactions, local new-growth vessels and proliferation of the nerve endings are also described.