Bridging Existing Energy and Chemical Transport Models to Enhance Air Quality Policy Assessment.

Connecting changes in emissions to air quality is critical for evaluating the effects of a specific policy. Here, we introduce a methodology to aid in assessing the air quality impacts of changes in the energy system. A set of widely varying scenarios that describe alternative potential evolutions of the US energy system is constructed using the TIMES energy system model.

Predictive Value of FDG Uptake on PET for Future Immune Checkpoint Inhibitor-Mediated Colitis: A Case Series.

: Immune-mediated colitis (IMC) is a common immune-related adverse event during immune checkpoint inhibitor (ICI) therapy. This case series and review aimed to highlight atypical cases of IMC and explore the potential of PET/CT to predict imminent ICI colitis. : Through a descriptive, retrospective study at a tertiary cancer center, we identified adult patients receiving ICIs for any cancer between 2010 and 2022 who also underwent PET/CT for routine cancer surveillance during this time.

[Lactic acidosis associated with metformin: A case series from the Saint-Denis hospital].

Introduction: Metformin is a first line treatment for type II diabetes. Cases of metformin-associated lactic acidosis are regularly reported. A direct causal link between metformin overdose and lactic acidosis is not clearly established.

Discovering Influenza Virus Neuraminidase Inhibitors via Computational and Experimental Studies.

Influenza A and B viruses spread out worldwide, causing several global concerns. Discovering neuraminidase inhibitors to prevent influenza A and B viruses is thus of great interest. In this work, a machine learning model was trained and tested to evaluate the ligand-binding affinity to neuraminidase.