Publications by authors named "S Neuburger"
Infectious complications after allogeneic haematopoietic stem cell transplantation (allo-HCT) remain a clinical challenge. This is a guideline provided by the AGIHO (Infectious Diseases Working Group) of the DGHO (German Society for Hematology and Medical Oncology). A core group of experts prepared a preliminary guideline, which was discussed, reviewed, and approved by the entire working group.
View Article and Find Full Text PDFDyskeratosis congenita (DC) is a rare inherited disorder characterized by the triad of nail dystrophy, mucosal leukoplakia, and reticular pigmentation. Bone marrow failure is the principal cause of early mortality, and stem cell transplantation is the only cure for these patients. However, the results of conventional hematopoietic stem cell transplantation (HSCT) for patients with DC are poor because of the high incidence of transplant-related complications.
View Article and Find Full Text PDFBackground: Limited data are available on characteristics of viral encephalitis in patients after allogeneic stem cell transplantation.
Design And Methods: We analyzed 2,628 patients after allogeneic stem cell transplantation to identify risk factors and characteristics of viral encephalitis.
Results: Viral encephalitis occurred in 32 patients (1.
Article Synopsis
- This study examined 93 patients with acute myeloid leukemia (AML) who underwent either reduced intensity conditioning (RIC) or standard myeloablative conditioning (MAC) before allogeneic stem cell transplantation (alloSCT).
- Results showed comparable overall survival (OS) and disease-free survival (DFS) rates between the RIC and MAC groups, with RIC demonstrating similar or better outcomes, especially in patients with intermediate-risk karyotypes.
- The findings suggest that RIC-alloSCT may provide stable remissions for AML patients in first complete remission (CR1), particularly for those with intermediate-risk profiles who may not tolerate the standard MAC treatment.
Background: BK virus-associated hemorrhagic cystitis (BKV-HC) is a severe complication after allogeneic hematopoietic stem cell transplantation (HSCT), but antiviral treatment for this condition has not been evaluated.
Methods: We conducted a retrospective survey on the safety and outcome of cidofovir treatment for patients with BKV-HC in centers affiliated with the European Group for Blood and Marrow Transplantation.
Results: From 1 April 2004 to 31 December 2007, 62 patients received a diagnosis of BKV-HC after a median interval of 35 days after HSCT (range, 3-577 days).