Publications by authors named "S Nestler"

Background: Acute rhinosinusitis (ARS) is a self-limiting inflammation of the nose and sinuses caused by viral or bacterial infections that requires primarily symptomatic treatment. Patient-reported outcome measures (PROMs) are suitable tools for the assessment of the effectiveness of remedies for ARS from the patient's perspective in clinical trials and real-world studies. Data regarding the quality of existing PROMs for ARS are limited.

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Response surface analysis (RSA) allows researchers to study whether the degree of congruence between two predictor variables is related to a potential psychological outcome. Here, we adapt RSA to the case in which the two predictor variables whose congruence is of interest refer to individual differences in within-person associations (WPAs) between variables that fluctuate over time. For example, a WPA-congruence hypothesis in research on romantic relationships could posit that partners are happier when they have similar social reactivities-that is, when they have similarly strong WPAs between the quantity of their social interactions and their momentary well-being.

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Sudden gains and sudden losses are abrupt, large changes in symptom severity between two consecutive psychotherapy sessions. Sudden gains (i.e.

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Multilevel structural equation modeling (MSEM) is a statistical framework of major relevance for research concerned with people's intrapersonal dynamics. An application domain that is rapidly gaining relevance is the study of individual differences in the within-person association (WPA) of variables that fluctuate over time. For instance, an individual's social reactivity - their emotional response to social situations - can be represented as the association between repeated measurements of the individual's social interaction quantity and momentary well-being.

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Background: Uncomplicated urinary tract infections (UTIs) in women are among the most common bacterial infections in primary care. Given the health threats related to the overuse of antibiotics, alternative options are of increasing importance. Patient-reported outcome measures are valuable tools for including the patients' perspective when evaluating the efficacy of these strategies.

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