Publications by authors named "S Nekolla"
Article Synopsis
- The study explores the use of a novel SPECT tracer, [Tc]-PentixaTec, to visualize CXCR4-positive immune cells in patients after an acute myocardial infarction (AMI).
- In a retrospective analysis of 9 AMI patients, increased CXCR4 expression was found in areas with reduced blood flow, indicating localized inflammation in the heart.
- The findings suggest that CXCR4 imaging could serve as a potential tool for assessing inflammation post-AMI, even though there was no significant correlation with common blood markers of heart damage.
Hybrid cardiovascular imaging. A clinical consensus statement of the european association of nuclear medicine (EANM) and the european association of cardiovascular imaging (EACVI) of the ESC.
Eur J Nucl Med Mol Imaging
October 2024
Article Synopsis
- - Hybrid imaging combines two or more imaging techniques to enhance image quality and information, particularly in cardiovascular applications.
- - This imaging can involve either merging images from separate scanners or using advanced hybrid machines like PET/CT and PET/MR.
- - The European associations aim to assess clinical scenarios that could benefit from this technology and suggest best practices for obtaining diagnostic images.
Impact of a dedicated cardiac protocol on diagnosis of infective endocarditis in patients undergoing [F]-FDG-thoracic digital-PET/CT - Effects of expertise level.
J Nucl Cardiol
September 2024
Background: This study aimed to assess the impact of dedicated cardiac protocol (DCP) on diagnostic accuracy of state-of-the-art digital [F]-FDG-PET/CT in infective endocarditis (IE) and the intra-individual comparison of the performance with that of conventional whole-body approach (WBA) and to analyze the effects of the expertise level of the investigators.
Methods: 44 patients suspected for IE underwent digital-FDG-PET/CT after overnight fasting. Each three consultants and trainees reread PET images blinded to the examination approach and clinical information.
Positron emission tomography/magnetic resonance (PET/MRI) hybrid imaging is now available for over a decade and although the quantity of installed systems is rather low, the number of emerging applications for cardiovascular diseases is still growing. PET/MRI provides integrated images of high quality anatomical and functional assessment obtained by MRI with the possibilities of PET for quantification of molecular parameters such as metabolism, inflammation, and perfusion. In recent years, sequential co-registration of myocardial tissue characterization with its molecular data had become an increasingly helpful tool in clinical practice and an integrated device simplifies this task.
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