Publications by authors named "S Negri"

The COVID-19 pandemic served as a catalyst to build a stronger European Health Union to protect the health of Europeans and to develop a new Global Health Strategy to contribute to global health security. In positioning itself as a key player in global health governance, the EU seeks to assert its responsibility as a global health actor and deepen its leadership in global health law.

View Article and Find Full Text PDF
Article Synopsis
  • Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women with BRCA1/2 pathogenic variants to prevent ovarian cancer, but many still refuse the surgery despite its benefits.
  • A study at a referral center in Italy analyzed 287 women, finding a high uptake rate of 96.1% for RRSO after counseling, although some women were hesitant due to fears about menopause and childbearing.
  • The study suggests that a specialized clinic with a supportive team and options for surveillance plays a crucial role in encouraging women to consider risk-reducing surgery.
View Article and Find Full Text PDF

Background: Granulosa cell tumors (GCTs) are rare neoplasia that account for less than 5 % of all the ovarian tumors. Juvenile GCT histotype is generally observed in adolescent and young women, representing a very rare disease, so only a paucity of data are present in literature. The aim of this study is to analyse the oncologic and fertility outcome in our case series of juvenile GCTs.

View Article and Find Full Text PDF

Background: The global demographic shift towards an aging population is generating a rise in neurodegenerative conditions, with Alzheimer's disease (AD) as the most prominent problem. In this landscape, the use of natural supplements has garnered attention for their potential in dementia prevention. Curcumin (Cur), derived from Curcuma longa, has demonstrated promising pharmacological effects against AD by reducing the levels of inflammatory mediators.

View Article and Find Full Text PDF