THE ROLE OF PSYCHOLOGICAL STRESS IN THE DEVELOPMENT OF ESSENTIAL ARTERIAL HYPERTENSION IN ELDERLY PEOPLE.

This article presents the results of a study of the correlation between psychological stress and essential arterial hypertension in elderly people living in a boarding house. The use of appropriate methods and materials, as well as the t-test to check the equality of the mean values in the two samples, allowed us to establish a certain causal relationship in the development of this disease.

HYPERHOMOCYSTEINEMIA AS A CAUSE OF ERECTILE DYSFUNCTION.

Hyperhomocysteinaemia (elevated blood levels of the amino acid homocysteine) attracted the interest of researchers in the middle of the 20th century. At first. Butz and du Vigneaud in 1932 described a disorder of methionine metabolism in children, which was manifested by homocysteinuria (homocysteine is not normally detected in the urine).

Germline CDKN1B variant type and site are associated with phenotype in MEN4.

Multiple endocrine neoplasia 4 (MEN4) is a rare multiglandular endocrine neoplasia syndrome clinically hallmarked by primary hyperparathyroidism (PHPT), pituitary adenoma (PitAd), and neuroendocrine tumors (NET), clinically overlapping MEN1. The underlying mutated gene - CDKN1B, encodes for the cell-cycle regulator p27. Possible genotype-phenotype correlations in MEN4 have not been thoroughly assessed.