Publications by authors named "S Narasaki"
: Airway management techniques, including mask ventilation and tracheal intubation, are vital across medical settings. However, these procedures can be challenging, especially when environmental conditions are less than ideal. This study explores how the height of the operating table affects the difficulty of anesthesia techniques involving mask ventilation and tracheal intubation.
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- Calphostin C (Cal-C) is a known protein kinase C (PKC) inhibitor that can inhibit PKC activation at low concentrations but activate it at high concentrations through a light-dependent mechanism.
- At low doses (<200 nM), Cal-C successfully stops PKC translocation and activation induced by certain compounds, while at higher doses (>2 μM), it raises intracellular calcium levels by mobilizing the endoplasmic reticulum (ER) without involving specific receptors.
- The study also found that high concentrations of Cal-C cause structural changes in the ER and generate singlet oxygen, which contributes to PKC activation and indicates its potential use in photodynamic therapy.
Diabetic neuropathic pain is a known complication of diabetes mellitus (DM) and results from the complex interaction of various factors affecting the nervous system. Yokuansan (YKS) is a versatile traditional Japanese herbal medicine with a wide range of applications, especially in pain management and neurological manifestations. YKS has analgesic properties for nerve damage and is a potential treatment for DM-induced neuropathic pain, especially in patients with diabetic neuropathy.
View Article and Find Full Text PDFBackground: We used transcatheter aortic valve implantation (TAVI) procedure time to investigate the association between surgical team maturity and outcome.
Methods: Among patients who underwent TAVI between October 2015 and November 2019, those who had Sapien™ implanted with the transfemoral artery approach were included in the analysis. We used TAVI procedure time and surgery number to draw a learning curve.
Transnasal humidified rapid-insufflation ventilator exchange (THRIVE) has been reported to have better efficacy during anesthesia induction compared to conventional mask ventilation, including improved oxygenation and prolonged safe apnea time. This study reports on the effectiveness of the THRIVE system during modified electroconvulsive therapy (mECT) for a patient experiencing severe hypoxia. A 78-year-old female patient with bipolar disorder received maintenance mECT every four weeks.
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