Publications by authors named "S Napravnik"
Article Synopsis
- Findings indicate that higher cumulative HIV viral load (VL) and lower CD4 cell counts are significantly linked to an increased risk of developing venous thromboembolism (VTE) in people living with HIV (PWH).
- A study involving over 21,000 PWH over nearly five years revealed that those with higher cumulative VL had a 45% increased risk of VTE compared to those with lower VL. Additionally, a CD4 count below 100 cells/mm³ was associated with a fourfold increase in risk.
- The research suggests that managing HIV viral load and maintaining CD4 levels could be crucial strategies to lower the risk of VTE in PWH.
Background: Attending clinic appointments supports HIV viral suppression, yet racial disparities are documented. We assessed whether multilevel resilience resources were associated with appointment attendance among African American/Black (AA/B) adults living with HIV in the United States.
Methods: We ascertained data from 291 AA/B clinical cohort participants from 2018 to 2021.
Substance use is associated with decreased antiretroviral therapy (ART) adherence among people with HIV (PWH). Adherence plays a significant role in mediating the negative effects of substance use on HIV suppression and is a principal modifiable patient-level factor in improving HIV suppression and reducing ART drug resistance. Understanding substance use and ART adherence, particularly with rapidly changing substance use epidemiology and ART regimens, is vital to improving HIV care.
View Article and Find Full Text PDFBackground: Frailty occurs at higher rates and younger ages among people with HIV (PWH) compared with the general population and is often attributed to chronic inflammation and subsequent immune exhaustion. We assessed how inflammatory biomarkers are associated with frailty among PWH.
Methods: The Centers for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS) cohort is comprised of adult PWH in care at 10 sites, and harmonizes demographic, clinical, and patient-reported outcomes (PRO) data.