3D printed dummy heads for crosstalk cancellation studies in bone conduction.

Thanks to affordable 3D printers, creating complex designs like anatomically accurate dummy heads is now accessible. This study introduces dummy heads with 3D-printed skulls and silicone skins to explore crosstalk cancellation in bone conduction (BC). Crosstalk occurs when BC sounds from a transducer on one side of the head reach the cochlea on the opposite side.

Relationship between kidney function and healthy life expectancy: A historical cohort study.

Background: The impact of chronic kidney disease (CKD) on healthy life expectancy and healthcare costs requires research. This study examined associations between CKD and healthy life expectancy, and its economic burden.

Methods: This study of community-dwelling adults residing in Hakui City, Ishikawa Prefecture, Japan used data from the National Health Insurance database between 2012 and 2022.

Negative DNA supercoiling enhances DARS2 binding of DNA-bending protein IHF in the activation of Fis-dependent ATP-DnaA production.

Oscillation of the active form of the initiator protein DnaA (ATP-DnaA) allows for the timely regulation for chromosome replication. After initiation, DnaA-bound ATP is hydrolyzed, producing inactive ADP-DnaA. For the next round of initiation, ADP-DnaA interacts with the chromosomal locus DARS2 bearing binding sites for DnaA, a DNA-bending protein IHF, and a transcription activator Fis.

Evaluation of gravity effect on liver and spleen volumes using multiposture MRI.

Liver and spleen volume measurements are important for early detection and monitoring of liver disease. However, alterations in liver and spleen volumes with postural changes, i.e.