Publications by authors named "S Nadadur"

Understanding the complex interplay of genetic and environmental factors in disease etiology and the role of gene-environment interactions (GEIs) across human development stages is important. We review the state of GEI research, including challenges in measuring environmental factors and advantages of GEI analysis in understanding disease mechanisms. We discuss the evolution of GEI studies from candidate gene-environment studies to genome-wide interaction studies (GWISs) and the role of multi-omics in mediating GEI effects.

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  • * The use of chemical warfare agents has increased in recent conflicts, raising concerns about the potential for industrial and agricultural chemicals being weaponized, especially near populated areas.
  • * Current regulations are insufficient to prevent inhalational injuries, and while emergency treatments exist, long-term complications can arise, necessitating ongoing medical care.
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  • * Environmental factors like pollutants and toxins can disrupt the body’s healing pathways, intensifying lung inflammation and possibly initiating diseases such as asthma and COPD.
  • * Continuous exposure to harmful substances not only worsens lung function but also contributes to persistent inflammation, suggesting that managing environmental toxins is critical for respiratory health.
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Atrial fibrillation (AF) is an established risk factor ischemic stroke (IS) and is commonly encountered in patient hospitalized with acute myocardial infarction (AMI). Uncommonly, IS can occur as a complication resulting from percutaneous coronary intervention (PCI). There is limited real world data regarding AF-associated in-hospital IS (IH-IS) in patients admitted with AMI undergoing PCI.

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