Publications by authors named "S NUMA"
Article Synopsis
- The study aims to find genetic factors that contribute to myopic macular neovascularization (mMNV) in people with severe myopia through a genome-wide association study (GWAS) meta-analysis.
- Researchers analyzed data from 2,783 highly myopic individuals, including 608 with mMNV and 2,175 controls, using advanced genetic analysis techniques.
- The study discovered a new genetic variant, rs56257842, associated with a lower risk of mMNV, and found that certain transcription factors interacted differently with this variant, suggesting it plays a significant role in the disease's development.
Article Synopsis
- - The study evaluated cellular changes in the foveal neuroglia of eyes with idiopathic epiretinal membrane (ERM) and their relationship with visual function post-vitrectomy, using adaptive optics OCT (AO-OCT) for analysis.
- - The research involved 84 subjects, comparing 50 eyes with ERM to 34 healthy control eyes, and analyzed various visual parameters before and after surgical intervention.
- - Key findings indicated that eyes with ERM displayed distinct alterations in foveal microstructures, including thicker ellipsoid zones and altered Müller cell alignment, both of which correlated with decreased visual function indicators.
Article Synopsis
- The study aimed to evaluate the effectiveness of genetic risk estimation in identifying primary open-angle glaucoma (POAG) among Japanese individuals through a cross-sectional analysis involving 3,625 participants.
- Genetic risk scores (GRSs) were developed based on a genome-wide association study, with the best-performing GRS comprising 98 significant variants showing strong predictive accuracy for POAG.
- Results indicated that individuals in the top 10% of GRS had a substantially higher likelihood of having POAG compared to those in the lowest 10%, highlighting the potential of GRS as a tool for glaucoma risk assessment in this population.*
Article Synopsis
- * The results showed that while patients with non-PM had better vision at 1 and 2 years compared to those with PM, by the 3rd and 4th years, their visual acuity (BCVA) was about the same for both groups.
- * However, patients with non-PM required significantly more injections over the 4-year period than those with PM, indicating they need closer monitoring and
Purpose: To evaluate the agreement between 24-2 visual field (VF) test results obtained using the gaze analyzing perimeter (GAP; Findex) and the Humphrey field analyzer (HFA; Carl Zeiss Meditec).
Design: Cross-sectional study.
Participants: Patients underwent HFA 24-2 for suspected or confirmed VF loss and were treated at the Kyoto University Hospital between December 2022 and July 2023.