[Using cytoflavin for correcting x-ray contrasting agent-induced nephropathy].

Experimental data on the influence of omnipak-350 introduction in a dose of 20 g/kg on the glutathione exchange processes and lipide peroxidation in kidneys, liver and erythrocytes of white outbred rats are presented. The possibility of using cytoflavin for correcting x-ray contrast agent-induced disorders in the natural cytoprotective system is shown. Probable mechanisms of the cytoprotective effect of the proposed pharmacological treatment are discussed.

[Cytoflavin in polychemotherapy of breast cancer].

The efficacy of cytoflavin as a supporting drug in the CAF chemotherapy of breast cancer was studied. It was estimated by the tolerability, the peripheric blood index dynamics, the patients general condition (Karnovsky Index) and the frequency of the side effects. For the immediate estimation of the polychemotherapy and cytoflavin effects on the cytoprotection natural system state, the dynamics of the glutathione metabolism and the lipid peroxidation in the erythrocytes was investigated.