[Gastric and duodenal ulcer disease: morphofunctional, neuroendocrine and clinical parallels].

Morphofunctional state of gastric mucous tunic and neuroendocrine cells, and clinical indices at various stages of gastric and duodenal ulcer disease was studied. It was shown, that in clinico-endoscopic remission stage of disease intensity of pathogenetic mechanisms of some neuroimmune-endocrine and clinical indices remained.

[The role of melatonin in pathogenesis of diseases of digestive system].

The problem of duodenal ulcer (DU) in one of the most important issues in gastroenterology. Successful eradication of Helicobacter pylori leads to a significant decrease in the frequency of DU recurrence. However, in spite of modern achievement, this disease cannot be cured completely.

[Antihelicobacter effects of melatonin].

The authors made an attempt to find a new approach to Helicobacter pylori (HP) eradication in patients with chronic gastritis and peptic ulcer without application of antibiotics, but using melatonin properties instead. The study demonstrates an undoubtful effect of melatonin as a preparation that favors HP eradication.