Publications by authors named "S N Rupasinghe"

Background: Anaemia is a global public health issue that impacts individuals of all ages in both developed and developing countries. Anaemia is common in patients with diabetes mellitus; however, it is often undiagnosed and untreated. The main aim of this study was to assess the prevalence and associated factors of anaemia in patients with type 2 diabetes mellitus admitting to a medical unit at National Hospital Kandy.

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Objective: To evaluate the Assistant in Medicine (AiM) programme and its impact on physician burden and productivity in the ED.

Methods: Calvary Mater Newcastle ED employed eight final year medical students as part-time AiMs for a 10-week period from October to December 2021. Each student worked one 10-h shift per week.

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Brain inflammation and apoptosis contribute to neuronal damage and loss following ischaemic stroke, leading to cognitive and functional disability. It is well-documented that the human gene-2 (H2)-relaxin hormone exhibits pleiotropic properties via its cognate receptor, Relaxin Family Peptide Receptor 1 (RXFP1), including anti-inflammatory and anti-apoptotic effects, thus making it a potential therapeutic for stroke. Hence, the current study investigated whether post-stroke H2-relaxin administration could improve functional and histological outcomes.

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Upper gastrointestinal tumours can metastasise to many viscera including the female reproductive system (Krukenberg tumour). However, spread to the male genitalia is extremely rare. We report the case of a man in his 70s who underwent oesophagogastrectomy for oesophagogastric junctional (OGJ) cancer with a complete response to neoadjuvant treatment who presented 4 months after completing treatment with a solitary testicular metastases.

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Hantaviruses are a large family of enveloped viruses with two medically important families Cricetidae and Muridae which are known to cause rodent-borne diseases worldwide. Some strains cause clinical syndromes with multiorgan involvement in humans such as hantavirus haemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS), which is also known as hantavirus pulmonary syndrome. Clinical differentiation of this infection from other endemic infections in Sri Lanka such as leptospirosis and rickettsial infections is extremely difficult due to overlapping clinical and epidemiologic features such as exposure to rodents and farming.

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