Single-Cell Transcriptomic Profiling Identifies Molecular Phenotypes of Newborn Human Lung Cells.

While animal model studies have extensively defined the mechanisms controlling cell diversity in the developing mammalian lung, there exists a significant knowledge gap with regards to late-stage human lung development. The NHLBI Molecular Atlas of Lung Development Program (LungMAP) seeks to fill this gap by creating a structural, cellular and molecular atlas of the human and mouse lung. Transcriptomic profiling at the single-cell level created a cellular atlas of newborn human lungs.

An Experimental Comparison of In-Person and Remote Instruction for Preschoolers with Disabilities.

Remote instruction is becoming increasingly common, yet few studies have directly compared remote and in-person instruction in a controlled manner. We used a reversal design to compare the effects of in-person and remote instruction for six preschool participants with disabilities learning tacts and sight words. Distribution of instruction, methodology, and materials across in-person and remote conditions were equated so that the only difference across conditions was the modality of instruction.

Family Perceptions of Participating in a Structured Summer Kindergarten Transition Program.

Many school districts provide one-time transition events to help students prepare for the rigors of kindergarten; yet, research shows families desire additional information and opportunities to help their children thrive once school begins. Researchers for this study interviewed 39 parents whose children participated in a three-week structured kindergarten transition program designed to promote parental involvement in school, reduce students' chronic absenteeism, and increase children's readiness for kindergarten. All interviewees expressed that participating in the program yielded benefits for themselves and their children.

Electrospun core-shell nanofibers with encapsulated enamel matrix derivative for guided periodontal tissue regeneration.

The osteogenic effect of a composite electrospun core-shell nanofiber membrane encapsulated with Emdogain (EMD) was evaluated. The membrane was developed through coaxial electrospinning using polycaprolactone as the shell and polyethylene glycol as the core. The effects of the membrane on the osteogenic differentiation of periodontal ligament stem cells (PDLSCs) were examined using Alizarin Red S staining and qRT-PCR.

A Comprehensive Multidisciplinary Management Plan Is Effective in Reducing the Prevalence of Overweight and Obesity in Childhood and Adolescence.

Background: Obesity in childhood and adolescence represents a major health problem of our century. In Greece, 30-35% of children and adolescents are overweight or obese. Objective and Hypotheses: To investigate the effectiveness of a comprehensive multidisciplinary personalized management plan at reducing the prevalence of overweight and obesity in childhood and adolescence.