Not all ST-segment elevations are myocardial infarction: Hyperkalemia and Brugada phenocopy.

Several clinical conditions other than Brugada syndrome (BrS) can mimic acute ST-segment elevation myocardial infarction and Brugada phenocopies are a part of those conditions that can mimic either true BrS or acute myocardial infarction. Our manuscript shows an interesting and didactic case report of type-1 Class A Brugada phenocopy (BrP) induced by hyperkalemia and allow us to teach the systematic approach to the proper diagnosis of BrP. A prompt recognition of this clinical and electrocardiographic entity may expedite the initiation of appropriate treatments as illustrated in this case report.

Medical liberty: drugless healers confront allopathic doctors, 1910-1931.

Education, medicine and psychotherapeutics offer exemplary sites through which liberty and its dreams are realized. This article explores the social history of medical freedom and liberty in North America during the late nineteenth and early twentieth centuries. The National League for Medical Freedom (NLMF) and the American Medical Liberty League (AMLL) offered fierce resistance to allopathic power.

[Activity of the kallikrein-kinin system of blood during combined treatment of patients with high and stable arterial hypertension].

The activity of the blood kallikrein-kinin system was evaluated in 18 patients with refractory arterial hypertension who received a combined therapy by using prostaglandin E2 (PGE2) infusions. PGE2 infusions produced a direct effect in modulating the vasoactive peptide system. There was activity mobilization at low baseline values of blood kallikrein and its inhibition at high values.

[Role of lipids in adaptive responses of the body to extreme exposure].

Experiments were conducted on 250 male albino rats to study the blood serum lipid spectrum in total-body dehydration, adrenalin-induced necroses of the myocardium, under the effect of transport noise with an equivalent level of 80-95 decibels and ultrashort-wave range electromagnetic field of 5-6 V/m intensity. In the early stages of exposure to the effect of extreme factors the change in lipid metabolism was monotypic in character and was manifested by hypercholesterolemia at the cost of the free fraction, increase of the level of triglycerides, free fatty acids and activity of lecithin-cholesterol acyltransferase, and reduction of the content of total phospholipids and disorders of their composition. These changes are associated with disturbed neurohumoral regulation and reflect the unspecific response of the organism to damage in the form of mobilization of lipids from the depot and switching metabolism from the carbohydrate to the lipid type.

[Changes in the phospholipid-phospholipid ratios and the enzyme activity of antioxidant protection in the rat lung during dehydration].

It was established that water deprivation during 3, 6, 9 days caused a distinct decrease in phospholipid level and disturbances of phospholipid composition in the rat lung tissue. It was accompanied by alterations in the activity of antioxidant defense system enzymes (superoxide dismutase, glutathione peroxidase, glutathione reductase, catalase, glucose-6-phosphate dehydrogenase). These data are indicative of lipid peroxidation intensification in the rat lungs during water deprivation.