Publications by authors named "S N Nematollahi-Mahani"
Tumor necrosis factor-α (TNF-α) induces a multitude of actions and consequences in bone and cartilage resorption and immune response augmentation. In this research, we aimed to investigate the effects of TNF-α on osteogenesis parameters in newborn mice. Experimental research was conducted on 42 pregnant mice, dividing into seven groups as follows: control (no injection), vehicle 1 (PBS injection on 7-9th pregnancy days (PD)), vehicle 2 (PBS injection during pregnancy), experimental 1 (injection of 10 ng/kg of TNF-α on 7-9th PD), experimental 2 (injection of 100 ng/kg of TNF-α on 7-9th PD), experimental 3 (injection of 10 ng/kg of TNF-α during pregnancy) and experimental 4 (injection of 100 ng/kg of TNF-α during pregnancy).
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- The median artery usually disappears after two months of fetal development but can persist into adulthood, sometimes associated with variations like a bifid median nerve.
- A cadaver study revealed a unique case with bilateral persistent median arteries (PMA) and a bifid median nerve, as well as an unusual origin and path for the palmar cutaneous branch of the median nerve (PCBMN).
- Dissection of a 45-year-old male cadaver showed that the PMA arose from the ulnar artery, leading to differing branching patterns in the hands, and highlighted the importance of recognizing these variations for understanding carpal tunnel syndrome and surgical risks.
Article Synopsis
- Different wavelengths from LEDs impact the growth and development of various cell types, particularly human umbilical cord matrix-derived mesenchymal cells (hUCMs), which are valuable in regenerative medicine and stem cell research.
- This study found that exposing hUCMs to green and red LED light significantly boosted the expression of genes and proteins associated with neural development, like nestin and β-tubulin III.
- Alternating between green and red light further enhanced the expression of these neural markers, indicating potential for future research into LED use for neural repair and regeneration therapies.
Granulosa cell insight: unraveling the potential of menstrual blood-derived stem cells and their exosomes on mitochondrial mechanisms in polycystic ovary syndrome (PCOS).
J Ovarian Res
August 2024
Background: Polycystic ovary syndrome (PCOS) presents a significant challenge in women's reproductive health, characterized by disrupted folliculogenesis and ovulatory dysfunction. Central to PCOS pathogenesis are granulosa cells, whose dysfunction contributes to aberrant steroid hormone production and oxidative stress. Mitochondrial dysfunction emerges as a key player, influencing cellular energetics, oxidative stress, and steroidogenesis.
View Article and Find Full Text PDFBackground: Exposure to physical contamination during chemotherapy, including non-ionizing electromagnetic fields, raises concerns about the widespread sources of exposure to this type of radiation. Glioblastoma multiforme (GBM) is an aggressive central nervous system tumor that is hard to treat due to resistance to drugs such as temozolomide (TMZ).
Objective: Electromagnetic fields (EMF) and haloperidol (HLP) may have anticancer effects.