Adverse events in India's Ayush interventions for cervical and lumbar spondylosis: a systematic review.

Introduction: Low back and neck pain are common musculoskeletal disorders with multiple treatment options. India's traditional medical systems, known as Ayush (Ayurveda, Yoga and Naturopathy, Unani, Siddha, Sowa-Rigpa and Homoeopathy) offer range of interventions and are widely used. In view of limited documentation of adverse events following Ayush interventions for lumbar and cervical spondylosis, we synthesized evidence and estimated proportion of studies reporting adverse events.

Microwave-assisted synthesis of crosslinked ureido chitosan for hemostatic applications.

In this study, we present a facile method for introducing hydrophilic ureido groups (NH-CO-NH-) into chitosan using a microwave-assisted reaction with molten urea, with the aim of enhancing chitosan's interaction with blood components for improved hemostasis. The formation of the ureido groups through nucleophilic addition reaction between the amine groups in chitosan and in situ generated isocyanic acid was confirmed by FTIR, CP/TOSS C NMR, and CP/MAS N NMR spectroscopic techniques. However, in stark contrast to the glucans, the said modification introduced extensive crosslinking in chitosan.

Surface exposed and charged residues drive thermostability in fungi.

Fungi, though mesophilic, include thermophilic and thermostable species, as well. The thermostability of proteins observed in these fungi is most likely to be attributed to several molecular factors, such as the presence of salt bridges and hydrogen bond interactions between side chains. These factors cannot be generalized for all fungi.

Improving Hydrophobicity of Collagen with Silica Nanoparticles: Probing a Noncovalent Approach.

Collagen-based materials have a wide range of applications in wound care, tendon repair, cartilage repair, etc. Improving certain properties such as hydrophobicity can diversify the application areas. In this work, we investigated the noncovalent interactions of suitably functionalized silica nanoparticles with collagen for the possibility of improving hydrophobicity.

Hyperglycemia and steroid use increase the risk of rhino-orbito-cerebral mucormycosis regardless of COVID-19 hospitalization: Case-control study, India.

Background: In the ongoing COVID-19 pandemic, an increased incidence of ROCM was noted in India among those infected with COVID. We determined risk factors for rhino-orbito-cerebral mucormycosis (ROCM) post Coronavirus disease 2019 (COVID-19) among those never and ever hospitalized for COVID-19 separately through a multicentric, hospital-based, unmatched case-control study across India.

Methods: We defined cases and controls as those with and without post-COVID ROCM, respectively.