This case report explains meticulous management of 5 year old, inferior alveolar nerve neuropathy, following placement of dental implants in the mandible. The imperative situation was that 'implants placed were not in contact with the nerve, but triggered neuralgic pain'. The objective of the treatment was to identify, and eliminate the causative factor, and to promote nerve regeneration, with pain relief.
View Article and Find Full Text PDFPurpose: The incidence of hepatocellular carcinoma (HCC) in the United Kingdom has increased 60% in the past 10 years. The epidemics of obesity and type 2 diabetes are contributing factors. In this article, we examine the impact of diabetes and glucose-lowering treatments on HCC incidence and overall survival (OS).
View Article and Find Full Text PDFBackground: The neutrophil-lymphocyte ratio (NLR), a presumed measure of the balance between neutrophil-associated pro-tumour inflammation and lymphocyte-dependent antitumour immune function, has been suggested as a prognostic factor for several cancers, including hepatocellular carcinoma (HCC).
Methods: In this study, a prospectively accrued cohort of 781 patients (493 HCC and 288 chronic liver disease (CLD) without HCC) were followed-up for more than 6 years. NLR levels between HCC and CLD patients were compared, and the effect of baseline NLR on overall survival amongst HCC patients was assessed via multivariable Cox regression analysis.