Publications by authors named "S N Bugrov"

Microscopic changes in the lung biopsies of 16 adult patients of both sexes without clear clinical symptoms are described. According to X-ray examination data, disseminated process in the lungs was diagnosed in 4 patients, interstitial pneumonia in 4, osteoplastic pneumopathy in 3, as well as tuberculosis, bronchiolitis and a number of others. Microscopic examination showed that the patients had various forms of petrification and ossification of the lungs, diagnosed clinically and radiologically in only 3 cases.

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The clinic and pathological anatomy of the infection caused by the SARS-CoV-2 virus (coronavirus infection - CI) with the development of Post-Covid syndrome (PS) have not been studied enough. This also applies to morphofunctional changes in the lungs, one of the most important components of PS. We conducted a histological and bacterioscopic study of lung biopsy specimens in 20 patients of both sexes aged 22-75 years.

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The article describes the clinical, radiological and pathological features of epithelioid hemangioendothelioma (EHE) in 27 adult patients, mainly female. In all cases, with the exception of one, there was a benign course of the disease over many years with a tendency to stabilize growth, the morphological sign of which was the development of widespread sclerotic changes. With the help of immunohistochemical method, the endothelial nature of EHE cells and its relatively low proliferative potential were confirmed.

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The goal of this paper was to estimate the predictive value of kinetic parameters of tumor growth in 109 prostatic cancer (PCa) patients with the morphologically verified diagnosis. The cell loss factor, calculated on the basis of Ki-67 values, and the PSA doubling time, proved to be an important prognostic parameter. A cumulative comparative analysis of these criteria, depending on the prevalence of the tumor process, indicates that the level of cell loss significantly decreases with increasing tumor stage ( = 1*10), and the growth rate of the tumor significantly increases ( = 1*10).

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A comparative analysis of lethality and causes of death of the burned in the Russian Burn Center of Ministry of Health of the Russian Federation for 40 years has shown that general lethality in the Burn Center for this period did not undergo substantial changes and was within 10%. Main causes of death were shock, sepsis and pneumonia. Other causes were of less significance.

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