The coronavirus disease 2019 pandemic substantially impacted the delivery of cancer services and programs. Here we reviewed and synthesized the global scale and impact of pandemic-related delays and disruptions on cancer services, including diagnosis, diagnostic procedures, screening, treatment and supportive and palliative care. Based on data from 245 articles in 46 countries, we observed declines in the number of cancer screening participation (39.
View Article and Find Full Text PDFDespite the high prevalence of anemia and malnutrition in Myanmar, the relationship between anemia and body mass index (BMI) remains underexplored. We analyzed nationally representative data from the Myanmar Demographic and Health Survey (MDHS) 2015-2016 to explore the effects of BMI on hemoglobin levels and anemia among children (n = 2,937) and women (n = 9,262). Anemia was defined as hemoglobin levels < 11 g/dl for children and pregnant women, and < 12 g/dl for nonpregnant women, with BMI categories classified according to WHO guidelines.
View Article and Find Full Text PDFAntenatal corticosteroids (ACS) are widely used to reduce respiratory distress syndrome (RDS) in preterm neonates, enhancing neonatal outcomes. However, the potential effects of ACS on other aspects of neonatal health, such as cortisol levels and glucose regulation, remain a concern. This study examines whether ACS administration impacts cortisol and glucose homeostasis in preterm infants by analyzing data from 14 selected studies.
View Article and Find Full Text PDFDespite the success of global vaccination campaigns, vaccine access in low-resource settings is an ongoing challenge. Subunit vaccines are a well-established and clinically scalable intervention, yet they have achieved limited success for poorly immunogenic antigens such as those associated with SARS-CoV-2. Delivery strategies that promote gradual release of subunit vaccines from the injection site offer the potential to improve humoral immunity by enhancing lymph node exposure, however, clinical implementation of this strategy is challenging due to poor scalability and high costs.
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