Ribociclib and palbociclib-induced erythema multiforme: a case report.

Cyclin-dependent kinase 4/6 inhibitors (CKIs), ribociclib, palbocilb and abemaciclib, have been approved in combination with endocrine therapy for the treatment of hormone receptor-positive and human epidermal growth factor 2-negative advanced or metastatic breast cancer. Severe dermatological adverse events are rare with these agents; however, they require direct recognition and management in order not to become life-threatening. Erythema multiforme (EM) belongs to a dermatopathic spectrum that includes immune-mediated, widespread hypersensitivity reaction, which occurs with varying degrees of severity and affects the skin and/or the mucosa.

Perceptions, emotional reactions and needs of adolescent psychiatric inpatients during the COVID-19 pandemic: a qualitative analysis of in-depth interviews.

Background: The new coronavirus pandemic (COVID-19) has been accompanied by severe psychological pressure on the entire population. However, little is known about how this pandemic could affect the more vulnerable population with severe mental illness.

Aims: To explore adolescent psychiatric inpatients' perceptions, emotional reactions and needs during the first wave of the COVID-19 pandemic.

Basal Ganglia Calcification: A Case Report of Fahr Disease With Pure Psychiatric Symptoms.

Fahr disease, also known as familial idiopathic basal ganglia calcification, is a rare neurodegenerative disorder, the etiology of which remains unknown. Given its various presentations, Fahr disease is presumed to be underdiagnosed and its prevalence underestimated. We present a case of Fahr disease that presented mainly with pure psychiatric symptoms.

CT image guided thermal ablation techniques for palliation of painful bone metastases.

Background: Many different treatment methods have been used for pain palliation in patients with bone metastases. The ideal treatment has to be fast, safe, effective and tolerable for the patient.

Objective: To evaluate the efficacy and safety of computed tomography (CT)-guided radiofrequency ablation (RFA) or microwave ablation (MWA) as a minimal invasive method of pain palliation.