Publications by authors named "S Muschik"
The nicotinic acetylcholine receptor (nAChR) is a pentameric ligand-gated ion channel (pLGIC) commonly used as a model for receptors belonging to the Cys-loop superfamily. Members of pLGICs are standardly used in numerous toxicological investigations e.g.
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- The treatment for poisoning from certain harmful chemicals, like nerve agents, is still hard to find because current medicines don't work very well.
- These toxic chemicals affect a crucial enzyme that helps our nerves communicate, which can lead to serious health problems and even death if not treated properly.
- Researchers are working on new tests to discover better medicines that can target specific parts of these toxins, using a special method that makes the testing process easier and faster.
Organophosphorus compounds (OPC), i.e. nerve agents or pesticides, are highly toxic due to their strong inhibition potency against acetylcholinesterase (AChE).
View Article and Find Full Text PDFDental anxiety is prevalent across a broad spectrum of the population. Dental phobia is extreme dental fear, which interferes with normal functioning. For any dental treatment, it is an ethical, legal and professional duty of dentists to obtain valid informed consent from their patients.
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