Publications by authors named "S Munoz-Fernandez"

Article Synopsis
  • The study aimed to analyze the characteristics and treatment responses of patients with uveitis related to immunologic or idiopathic diseases needing immunosuppressive therapy.* -
  • A total of 356 patients were reviewed; 12% received systemic corticosteroids, while 18.5% required immunosuppressive or biological treatments, mostly with methotrexate and adalimumab.* -
  • Findings concluded that many patients needed immunosuppressive therapy, and while several drugs were used, tocilizumab showed notable effectiveness in resolving macular edema.*
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Objective: Malnutrition is one of the most threatening conditions in geriatric populations. The gut microbiota has an important role in the host's metabolic and muscular health: however, its interplay with disease-related malnutrition is not well understood. We aimed to identify the association of malnutrition with the gut microbiota and predict clinical outcomes in hospitalized acutely ill older adults.

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Article Synopsis
  • The study aimed to assess the prevalence of SARS-CoV-2 antibodies in patients with immune-mediated inflammatory diseases (IMID) who are receiving biologic or synthetic therapies.
  • Conducted from October 2020 to May 2021, researchers evaluated 550 patients and found an overall seroprevalence rate of 16%, with higher rates in those treated with tumor necrosis factor alpha inhibitors (TNFi).
  • The findings also indicated that concurrent treatment with methotrexate reduced the seroprevalence in patients taking TNFi, suggesting a complex interaction between therapies affecting immune response.
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Post-COVID-19 interstitial lung disease (ILD) is a new entity that frequently causes pulmonary fibrosis and can become chronic. We performed a single-center parallel-group open-label pilot randomized clinical trial to investigate the efficacy and safety of cyclosporine A (CsA) in the development of ILD in the medium term among patients hospitalized with COVID-19 pneumonia. Patients were randomized 1:1 to receive CsA plus standard of care or standard of care alone.

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Article Synopsis
  • Spondyloarthritis (SpA) is a group of related diseases, including axSpA and psoriatic arthritis (PsA), but there isn't much real-world information about them.
  • The study aimed to look into the characteristics and treatment of axSpA and PsA patients using data from hospitals and fancy computer technology.
  • Out of 887,735 patients, 758 were chosen for the study, revealing that many didn't have clear disease activity scores, which are important for understanding how serious their condition is.
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