Publications by authors named "S Mukerji"

Background: This study examined the relationship between neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) and cognition in people living with HIV (PLWH) at baseline and over time.

Methods: Plasma and clinical data were available from PLWH aged ≥45 years with HIV RNA <200 copies/mL enrolled in the AIDS Clinical Trials Group HAILO cohort study. We measured plasma NfL and GFAP using a single molecule array platform.

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Article Synopsis
  • Unstructured and structured data in electronic health records (EHR) can provide valuable insights for research, but extracting this information can be challenging; researchers introduced an automated model to identify patients with Alzheimer's Disease, related dementias (ADRD), and mild cognitive impairment (MCI).
  • The study involved a sample of 3,626 outpatient adults, using medical notes and diagnoses from chart reviews to develop a logistic regression model that predicts MCI/ADRD diagnoses with high performance metrics.
  • The model demonstrated impressive accuracy (99.88%) and other metrics (like AUROC of 0.98), showing that automated EHR phenotyping could effectively facilitate large-scale research on MCI/ADRD.
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Objective: To determine whether balloon dilation of Eustachian tube (BDET) improves postoperative audiology and quality of life scores in children with chronic Eustachian tube dysfunction.

Study Design: Retrospective study.

Setting: Tertiary care pediatric center.

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