Osteosarcoma is a frequently occurring primary skeletal malignancy in the adolescent population. It arises from primitive mesenchymal bone forming cells and frequently involves long bones near the metaphyseal growth plate. Multiple imaging modalities are used for complete staging workup at the time of presentation; including magnetic resonance imaging (MRI) for local disease extent, computed tomography (CT) scan to rule out pulmonary metastasis, and bone scan to look for distant osseous metastases.
View Article and Find Full Text PDF18F-FGD PET-CT scan has a well-established role in staging and restaging gastrointestinal tract carcinomas and less commonly for bladder malignancies. FDG detects tumours by the presence of increased metabolic activity in tumour cells showing as foci of increased uptake on the scan. Bladder malignancy is often masked by physiological excretion of radiotracer into the urinary bladder.
View Article and Find Full Text PDFBleomycin, an antitumour antibiotic, is an essential part of treatment for multiple curable cancers, most commonly Hodgkin Lymphoma (HL) and germ cell tumours. Major limitation of its use is lung toxicity. Early diagnosis and treatment of bleomycin lung toxicity (BLT) is crucial, as the changes are reversible during early inflammatory phase only.
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