Publications by authors named "S Muftuoglu"
Article Synopsis
- The Hedgehog signaling pathway is important for folliculogenesis, but its relationship with FF-MAS oxysterol in this process, especially in conditions like PCOS, is not well understood.
- *The study found that FF-MAS enhances the proliferation of granulosa cells (GCs) and increases key Hedgehog pathway components (SMO and Gli1) even in the presence of an inhibitor, suggesting its significant role in follicular development.
- *Ultimately, this research could lead to new strategies for improving human IVF treatments by leveraging FF-MAS's effects on GCs and folliculogenesis.
Objectives: This study is aimed to evaluate the cleaning efficacy of five different irrigation systems as SonicMax, RinsEndo, EndoVac, passive ultrasonic irrigation (PUI), and manual needle irrigation (MNI) to histologically evaluate the presence of organic structures and the penetration of irrigation solution.
Materials And Methods: Forty-two single-rooted, extracted human mandibular premolars were used in the study. Each tooth was decoronated at the cementoenamel junction and the root canals were instrumented using ProTaper rotary instruments in a crown-down manner.
Purpose: Patients with polycystic ovarian morphology (PCOM) make up 20% cases for assisted reproductive technology (ART). Folliculogenesis is impaired in PCOS. Signaling molecules are involved in follicle development.
View Article and Find Full Text PDFBackground: Doxorubicin (dox) is a chemotherapeutic agent widely used against various tumors. However, the clinical use of this agent is limited due to various organ toxicities. Taurine is an intracellular free β-amino acid with antioxidant properties.
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