Calculating evidence-based renal replacement therapy - Introducing an excel-based calculator to improve prescribing and delivery in renal replacement therapy - A before and after study.

Background: Transferring the theoretical aspect of continuous renal replacement therapy to the bedside and delivering a given "dose" can be difficult. In research, the "dose" of renal replacement therapy is given as effluent flow rate in ml kgh. Unfortunately, most machines require other information when they are initiating therapy, including blood flow rate, pre-blood pump flow rate, dialysate flow rate, etc.

Ciprofloxacin levels in a patient undergoing veno-venous haemodiafiltration.

Haemofiltration is a popular technique for removal of fluid and small to medium size molecules in critically ill patients. Whilst there is often good information on drug disposition in chronic renal failure, there is a lack of information available to guide Intensivists on how to prescribe drugs in patients in acute renal failure undergoing haemofiltration or haemodiafiltration.

Comparison of the effects of dopamine, dobutamine, and dopexamine upon renal blood flow: a study in normal healthy volunteers.

1. We compared the effects of dopexamine, dopamine and dobutamine on the heart rate, blood pressure and renal blood flow of six healthy volunteers in an open triple crossover trial. 2.