Background: Clostridioides difficile infection (CDI) is an infectious disease caused by the gram-positive, anaerobic bacterium C. difficile. The vulnerable populations for CDI include the elderly, immunocompromised individuals, and hospitalized patients, especially those undergoing antimicrobial therapy, which is a significant risk factor for this infection.
View Article and Find Full Text PDFObjectives: Due to nano-dimensions (less than 100 nm), can nanoparticles probably penetrate through various membranes and travel from the bloodstream to other organs in the body. The aim of our study was to find out whether NPs FeO (coated with sodium oleate) injected into the tail vein of laboratory Wistar rats pass through the bloodstream to the respiratory tract (in comparison with a control group); and if so whether increasing doses of NPs FeO have an escalating harmful effect on selected bronchoalveolar lavage (BAL) parameters.
Methods: Wistar rats were intravenously given 3 doses of the suspension of NPs FeO (0.
Objective: Nanomaterials consist of particles smaller than 100 nm - nanoparticles (NPs). Their nano dimensions allow them to penetrate through various membranes and enter into the bloodstream and disseminate into different body organs. Massive expansion of nanotechnologies together with production of new nanoparticles which have not yet been in contact with living organisms may pose a potential health problem.
View Article and Find Full Text PDFObjective: Nanomaterials are materials consisting of particles having one or more dimensions smaller than 100 nm. Nanoparticles (NP) have different properties and effects in comparison with the same particle materials of larger size. They can penetrate through various membranes and get from the bloodstream to other organs in the body.
View Article and Find Full Text PDFIntroduction: In the medical field, nanoparticles (NP) Fe3O4 are currently considered to be a relatively inert carrier for therapeutic and diagnostic pharmaceuticals, and they are also presumed for intravenous (i.v.) administration.
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