Publications by authors named "S Moravcova Balkova"

Article Synopsis
  • Mammals have different types of teeth (heterodonty) with simpler teeth in the front and more complex ones in the back, and this study looks at the genes involved in their early development.
  • Researchers analyzed gene expression patterns in the lower jaw of mice at two early development stages, finding significant differences in signaling molecules (like BMP and FGF) between the front and back regions of the jaw.
  • The study highlights the role of the SATB2 gene in developing incisor teeth and its surprising expression near molars, indicating that gene functions can vary significantly depending on the jaw's location.
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This work evaluates the impact of the COVID-19 pandemic on Czech dentistry from March 2020 to March 2021. The assessment was based on questionnaires filled out by 3674 Czech dentists representing 42.6% of practicing dentists in the country.

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Ecotropical viral integration site 1 (Evi-1) is a transcription factor essential for vascularisation and cell proliferation during embryonic development. The chimeric transcription factor AML1-EVI-1 is activated in leukaemia where it plays a role as a differentiation block and stimulator of proliferation. Here, we cloned chicken Evi-1 and analysed its expression during embryonic development.

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Objective: Replacement teeth in reptiles and mammals develop from a successional dental lamina. In monophyodont (single generation) species such as the mouse, no successional lamina develops. We have selected a reptilian monophyodont species - the Veiled Chameleon (Chamaeleo calyptratus) - to investigate whether this is a common characteristic of species that do not have replacement teeth.

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The transcription factor c-Myb is involved in the control of cell proliferation, survival and differentiation. As these processes accompany the morphogenesis of developing teeth, this work investigates the possible role of c-Myb during odontogenesis. Analysis of the expression of c-Myb in the monophyodont mouse was followed by similar analysis in a diphyodont species, the pig, which has a dentition more closely resembling that of the human.

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