Gold nanoparticles, paclitaxel (PTX), and camptothecin (CMPT) were loaded into the PVA/κ-carrageenan/pegylated-PU composite and core-shell nanofibers prepared by two-nozzle and coaxial electrospinning methods. The capability of composite and core-shell nanofibers was investigated for the targeted delivery of anticancer drugs in lung cancer treatment. and release of PTX and CMPT were investigated to find the release mechanism from nanofibers compared to direct administration of pristine PTX and CMPT.
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