In silico pace mapping identifies pacing sites more accurately than inverse body surface potential mapping.

Background: Electrocardiographic imaging (ECGi) is a noninvasive technique for ventricular tachycardia ablation planning. However, it is limited to reconstructing epicardial surface activation. In silico pace mapping combines a personalized computational model with clinical electrocardiograms (ECGs) to generate a virtual 3-dimensional pace map.

Corrosion Inhibition of Mild Steel by Coumarate-Based Ionic Liquids and Coatings.

The use of ionic liquids (ILs) as corrosion inhibitors is gaining significant attention due to their attractive properties such as high inhibition efficiency and ability to absorb onto metal surfaces. In this work, six protic ILs, based on the coumarate anion in combination with the nitrogen containing ammonium, pyrrolidinium and imidazolium cations with a short or long alkyl chain attached to the nitrogen atom, have been synthesized and evaluated as corrosion inhibitors for mild steel. The anticorrosion properties of these ILs in solution as inhibitors were investigated electrochemically and the metal surface was analyzed by Scanning Electron Microscopy.

Targeting hypoxia signaling pathways in angiogenesis.

Oxygen (O) supply is constantly maintained by the vascular network for a proper tissue oxygenation. Hypoxia is the result of an increased O demand and/or decreased supply and is common in both physiological conditions and human diseases. Angiogenesis is one of the adaptive responses to hypoxia and is mainly regulated by the hypoxia-inducible factors, HIFs.