Preparation of bovine serum albumin nanospheres desolvation: a study of synthesis, characterization, and aging.

Serum albumin has myriad uses in biotechnology, but its value as a nanocarrier or nanoplatform for therapeutics is becoming increasingly important, notably with albumin-bound chemotherapeutics. Another emerging field is the fabrication of biopolymeric nanoparticles using albumin as a building block to achieve highly-tunable nonimmunogenic capsules or scaffolds that may be cheaply and reliably produced. The aim of this study was to characterize and optimize the desolvation process used for fabrication of albumin nanoparticles under ambient conditions, studying both glutaraldehyde (GT) and glucose (GLU) as crosslinking agents and the effect of various synthesis conditions including pH, electrolyte concentration, and rate of desolvation on particle size and stability.

Tuning the Chemistry of Fe-Nodes in MIL-100(Fe) through In Situ Generation of High Ratio of Mixed-Valence Sites: The Roles of Site-Specific and Textural Properties in Photo-Fenton Reaction.

Several studies were focused on the application of MIL-100(Fe) (FeO(OH)(HO)(BTC), HBTC is 1,3,5-benzene tricarboxylic acid) in the photo-Fenton reaction, but it still suffers from low efficiency. In this work, MIL-100(Fe) was synthesized at ambient conditions and low pHs using Fe(II) precursors in homogeneous aqueous media to develop a sample with high activity in the photo-Fenton reaction, even better than Fe-porphyrin metal-organic frameworks. The as-synthesized sample is highly crystalline with 30.

High efficiency high gain low side lobe level and slant polarization monopulse antenna using cavity backed slot coupled patch antenna.

In this paper, a multilayer monopulse antenna at Ku-Band with high efficiency, high power handling capability, high gain, 45° linear polarization and low sidelobe is presented. A new slot antenna is proposed as a radiating element based on a cavity-backed slot-coupled patch antenna. Using an enclosed cavity structure reduces coupling between antenna elements, thus increasing the antenna efficiency.

The Effect of Biofeedback on Constipation, Sleep, Depression, Anxiety and Quality of Life in Patients with Dyssynergic Defecation: a QUASI Experimental Study (Before and After Study).

Dyssynergic defecation(DD) is the inability to coordinate abdominal and anorectal muscle contraction during defecation. Patients with constipation often report poor quality of life, sleep issues, and increased risk of mood disorders. Biofeedback is a recommended treatment for DD.

Inhibitory effects of nafcillin and diosmin on biofilm formation by Salmonella Typhimurium.

Objective: The foodborne pathogen Salmonella enterica serovar Typhimurium causes self-limiting gastroenteritis in humans and is difficult to eliminate due to its ability to adhere to surfaces and form biofilms that exhibit high resistance to antimicrobial agents. To explore alternative strategies for biofilm treatment, it is essential to investigate novel agents that inhibit Salmonella biofilms.

Method: In this study, we investigated the minimum biofilm inhibitory concentrations (MBICs) and minimum biofilm eradication concentrations (MBECs) of nafcillin and diosmin, both previously identified as Lon protease inhibitors, against biofilms formed by S.