Publications by authors named "S Mohammad Jafri"

Rural health disparities in Texas impact population health due to limited healthcare access, insurance, and transportation challenges, especially in medically underserved areas. A shortage of specialists in rural regions worsens these issues, leading to increased morbidity and mortality rates. Our research aimed to address a knowledge gap by investigating the availability of three medical specialists-cardiologists, pulmonologists, and endocrinologists-in rural counties of Texas and identifying areas where access to healthcare is limited.

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  • Patients who have undergone solid organ transplants are at higher risk for severe COVID-19 due to immunosuppressive therapy, necessitating better vaccination and treatment strategies.
  • A study assessed the outcomes of liver and kidney transplant recipients diagnosed with COVID-19, focusing on factors like vaccine doses and monoclonal antibody (mAb) therapy.
  • Results showed that while some vaccine doses had no impact, liver transplant patients on mycophenolate had significantly higher mortality rates, and those receiving mAb therapy had lower hospitalization rates, highlighting the need for tailored treatment approaches in this vulnerable group.*
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Background: As calcineurin inhibitors are associated with renal impairment post intestinal transplant, use of everolimus (EVR) may provide renal-sparing benefits.

Methods: We performed a retrospective analysis focused on EVR use and renal function after intestinal or multivisceral transplant. No prisoners were used in the study.

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BACKGROUND Small bowel transplantation (SBT) is a rare but life-saving surgery. However, successful full-term pregnancies in individuals with SBT are exceedingly rare due to the nutritional and immunosuppression challenges this transplant poses for pregnancy. Therefore, clear guidelines for treating pregnant SBT recipients are unavailable.

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  • The study evaluated the effects of melatonin on the immune system of immunosuppressed male Wistar rats by measuring levels of Interleukin 6 (IL-6), total leucocyte counts (TLC), and different types of white blood cells.
  • Experiments involved treating groups of rats with cyclophosphamide and melatonin over a specified period and assessing the immune responses through blood tests.
  • Findings indicated that melatonin significantly increased IL-6 and TLC levels, suggesting it may help enhance immune functions in immunosuppressed states compared to other immunomodulators.
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