Publications by authors named "S Mohammad Ahmadi Soleimani"
Background: Triple-negative breast cancer (TNBC) is highly invasive and metastatic to the lymph nodes. Therefore, it is an urgent priority to distinguish novel biomarkers and molecular mechanisms of lymph node metastasis as the first step to the disease investigation. Long non-coding RNAs (lncRNAs) have widely been explored in cancer tumorigenesis, progression, and invasion.
View Article and Find Full Text PDFThere is always a concern about the quality of cell-based products in terms of the contamination of the cells and their lack of efficiency. Therefore, it is of prime importance to ensure these cells' identity, purity, efficacy, and suitability for the production of biological products and diagnostic uses. Hence, cells must be identified, evaluated, documented, and stored to be used consistently and efficiently.
View Article and Find Full Text PDFBackground: Systemic lupus erythematosus is a multi-organ autoimmune disorder that is treated by immunosuppressive agents that weaken the immune defense against opportunistic pathogens and latent infections such as strongyloidiasis. Herein, we report the case of a 43-year-old woman known to have systemic lupus erythematosus who presented with gastrointestinal symptoms, edema, and bone pain 2 months after receiving immunosuppressive treatment.
Case Presentation: A 43-year-old Iranian female known to have systemic lupus erythematosus and antiphospholipid syndrome presented with abdominal pain, nausea, vomiting, and generalized edema.
Article Synopsis
- A study was conducted to evaluate the effects of aspirin on bleeding during arteriovenous fistula (AVF) placement surgery in end-stage renal disease patients, particularly addressing whether discontinuing aspirin is necessary before the surgery.
- The research involved 60 patients, split evenly between those who took 80 mg of aspirin daily and those who did not, with outcomes focusing on blood loss and AVF success.
- Results showed no significant differences in bleeding, operation duration, or AVF outcomes between the two groups, suggesting that patients can continue aspirin use without adverse effects during the surgery, while further research is encouraged.
Article Synopsis
- TNF-α is a multifunctional cytokine essential in immune regulation and inflammation but is also linked to chronic diseases, including digestive cancers, due to its roles in cell growth and autoimmunity.
- It interacts with two receptors, TNFRI and TNFRII, activating signaling pathways that can lead either to cell survival (via NF-kB) or apoptosis (through TNF RI and Fas L).
- The review highlights that gastrointestinal cancers are increasing in incidence and are typically diagnosed late, with TNF-α and similar growth factors playing significant roles in their development and spread.