Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia.

Aim: Rising prevalence of Type 2 Diabetes (T2D) among young Asians has emerged as a public health crisis that threatens the long-term health, economic stability, and productivity of nations across Asia (1). Early-onset T2D poses unique challenges, including higher rates of undiagnosed cases, more aggressive disease progression, an increased risk of chronic complications and higher mortality (2). Hyperglycemia during the reproductive age especially among the female population can potentially have transgenerational impact through epigenetic changes.

Orbital metastasis of renal cell carcinoma masquerading as thyroid ophthalmopathy.

Renal cell carcinoma (RCC) is the most common kidney malignancy in adults. However, its presentation with orbital metastasis as the first clinical manifestation is extremely rare and can mimic several other conditions. We report the case of a 72-year-old woman with a history of hyperthyroidism, who presented with symptoms resembling thyroid ophthalmopathy.

Van Wyk-Grumbach Syndrome with bilateral inguinal hernia: A case report.

Introduction: Van Wyk-Grumbach Syndrome (VWGS) is a rare pediatric endocrinological disorder characterized by hypothyroidism, delayed bone age, enlarged multicystic ovaries, and precocious puberty. It results from prolonged hypothyroidism, affecting the hypothalamic-pituitary-gonadal axis. This report describes a 7-year-old girl presenting with vaginal bleeding and abdominal pain, leading to a diagnosis of VWGS with bilateral inguinal hernia and requiring surgical intervention.