Publications by authors named "S Misono"
Characterization of upper esophageal sphincter pressures relative to vocal acoustics.
J Appl Physiol (1985)
January 2025
Strength of vocal fold adduction has been hypothesized to be a critical factor influencing vocal acoustics but has been difficult to measure directly during phonation. Recent work has suggested that upper esophageal sphincter (UES) pressure, which can be easily assessed, increases with stronger vocal fold adduction, raising the possibility that UES pressure might indirectly reflect vocal fold adduction strength. However, concurrent UES pressure and vocal acoustics have not previously been examined across different vocal tasks.
View Article and Find Full Text PDFCurrent opinion in refractory and/or unexplained chronic cough.
Curr Opin Otolaryngol Head Neck Surg
December 2024
Article Synopsis
- Otolaryngologists play a crucial role in the management of chronic cough in adults, and this review highlights recent developments in our understanding of the condition.
- There has been significant research growth revealing the psychosocial effects of chronic cough and clarifying its complex neural mechanisms in both normal and abnormal situations.
- Future trends suggest a shift towards personalized treatments for chronic cough, incorporating various pharmacological and behavioral therapies, as well as a focus on multidisciplinary collaboration among healthcare professionals.
Article Synopsis
- The PACIFIC trial established durvalumab as the standard treatment after chemoradiotherapy for unresectable locally advanced nonsmall cell lung cancer (LA-NSCLC), but its effects on patients aged 75 and older were unclear.
- A study reviewed 214 patients on durvalumab and used propensity score matching to assess its efficacy in elderly patients, revealing 2-year progression-free survival (PFS) at 42.2% and overall survival (OS) at 77.1%.
- Although older patients had a significantly shorter OS compared to younger ones, the effectiveness for disease control was similar across age groups, and the treatment was tolerated well by elderly patients, supporting durvalumab's use in this population.
Objectives: Unexplained chronic cough (UCC) is common and has significant impacts on quality of life. Ongoing cough can sensitize the larynx, increasing the urge to cough and perpetuating the cycle of chronic cough. Vibrotactile stimulation (VTS) of the larynx is a noninvasive stimulation technique that can modulate laryngeal somatosensory and motor activity.
View Article and Find Full Text PDFThis case series examines seven patients diagnosed with cricoid chondronecrosis after intubation in the setting of COVID-19 and presents a novel "cricoid chondronecrosis computed tomography (CT) grading rubric" to standardize reporting of radiological findings. Application of this radiological grading rubric can improve communication among clinicians and radiologists and aid in prognosis determination of patients with cricoid chondronecrosis. Laryngoscope, 135:251-256, 2025.
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