[Surgical tactics at acute colonic bleedings].

The analysis of complex clinical examination of 134 patients with acute colonic bleeding treated at Medical Centre "St. Grigor Lusavorich" in Yerevan during last 12 years is presented. It was found that causes of acute colonic bleeding are very diverse.

[The characteristic of humoral non-specific defence factors in patients with mechanic jaundice according to the methods of drainage of biliary tracts].

The aim of the article was the evaluation of the efficiency of decompression of biliary tracts and determination of optimal period of external draining. The biochemical rates of functional state of liver, dynamic of factors of humeral nonspecific defense in blood serum and bile, in 197 patients with obstructive jaundice were investigated. Concurrently, the dynamic of nonspecific defense reaction changes in infected hepatic bile, changes of amylase, pH, and bile hypertensia were studied.

[Preparation for the surgery and surgical treatment for complicated abdominal hernias].

The analysis of surgical treatment of 98 patients with complicated ventral hernias showed that in preparation for the surgery should be conducted ultrasound investigation, thorough preparation for surgery with dynamic pneumatic compression, as well as measures to avoid purulent inflammatory complications during the surgery and post operation period, improves the outcome of treatment of ventral hernia.

[Early compensation for the loss of bile during external drainage].

The article presents the results of treatment of mechanical jaundice; 115 patients with mechanical jaundice were treated by Choledochotomy; in 92 cases external drainage after Choledochotomy was employed. It was found that early and adequate decompression of gall ducts decreases postoperative complications. The investigation showed that the frequency of early post-operative complications are directly connected with daily external bile loss in patients with external drainage of gall ducts.

[Effect of beditine on the cerebral circulation and various metabolic parameters].

Beditin, or 2-(2-amino-4-thiazolyl)-1,4-benzodioxane hydrochloride, is a new benzodioxane derivative possessing antihypoxant and alpha 2-adrenoreceptor blocker properties. In contrast to idazoxan, a well-known alpha 2-adrenoreceptor blocker, beditin (3 mg/kg) significantly increases the circulation rate and decreases the blood vessel resistance in various brain structures of rats and cats without considerably changing their systemic hemodynamic indices. Upon a one-side ligation of the common carotid artery in rats, beditin prevented a sharp increase in the lactate dehydrogenase activity and a growth in the content of free ammonia in the brain, which are characteristic of the ischemic states.