Publications by authors named "S Miguel"
Article Synopsis
- The text discusses the impact of pneumococcal conjugate vaccines (PCVs), specifically PCV10 and PCV13, on invasive pneumococcal disease (IPD) globally, highlighting how these vaccines have reduced the prevalence of disease caused by vaccine-type serotypes after extensive use.
- It describes the methodology of data collection from various surveillance sites, which aimed to evaluate IPD cases that occurred five years after the vaccines were implemented, focusing on different age groups for analysis.
- Findings indicate significant differences in serotype distribution between PCV10 and PCV13 sites; notably, certain serotypes, such as 19A and serotype 3, were prevalent in specific age groups, signaling ongoing challenges in controlling
Background: Surgical site infection (SSI) prevention bundles have been used to reduce infection rates in most types of surgery. Bundles tailored to colorectal surgery have been used with success.
Aim: To identify and review the individual interventions that constitute each SSI prevention care bundle in colorectal surgery, and the reduction in SSI rate associated with their implementation.
Unprecedented selectivity behavior in the direct dehydrogenation of -butane to -butenes with similar active Pt nanoparticle size: unveiling structural and electronic characteristics of supported monometallic catalysts.
Phys Chem Chem Phys
October 2024
In this work, supported Pt monometallic catalysts were prepared using oxide and carbon supports by conventional impregnation methods. Similar Pt metallic nanoparticle sizes (mean sizes about 1.8-2 nm) have been obtained using different Pt precursor loadings (0.
View Article and Find Full Text PDFMonoclonal antibodies (mAbs) have revolutionized the landscape of cancer therapy, offering unprecedented specificity and diverse mechanisms to combat malignant cells. These biologic agents have emerged as a cornerstone in targeted cancer treatment, binding to specific antigens on cancer cells and exerting their therapeutic effects through various mechanisms, including inhibition of signaling pathways, antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and antibody-dependent cellular phagocytosis (ADCP). The unique ability of mAbs to engage the immune system and directly interfere with cancer cell function has significantly enhanced the therapeutic armamentarium against a broad spectrum of malignancies.
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- * Analysis of data from over 1 million forest plots and thousands of tree species shows that wood density varies significantly by latitude, being up to 30% denser in tropical forests compared to boreal forests, and is influenced mainly by temperature and soil moisture.
- * The research also finds that disturbances like human activity and fire alter wood density at local levels, affecting forest carbon stock estimates by up to 21%, emphasizing the importance of understanding environmental impacts on forest ecosystems.