Publications by authors named "S Miglani"

Background: Emergency Front of Neck access eFONA) via cricothyroidotomy using a size 6 internal diameter tracheal tube is recommended by the Difficult Airway Society in the event of a 'can't intubate, can't oxygenate' (CICO) scenario in adults. There is a lack of clear guidance on whether to retain or remove a previously inserted supraglottic airway device (SAD) before eFONA. We aimed to study the effect of both neck extension and insertion of an SAD on sagittal cricothyroid membrane (CTM) height.

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Aims: People with disabilities (PWD) often face more significant oral healthcare needs than the general population. This study, conducted in response to the urgent and pressing need for improved dental care for PWD, aims to assess the infrastructural and work process flow of dental centers in Delhi that provide specialized dental care for PWD.

Methods And Results: A descriptive cross-sectional study was conducted across primary, secondary, and tertiary healthcare centers in Delhi, evaluating their infrastructure adaptations and work processes in delivering oral healthcare to PWD.

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Article Synopsis
  • The study investigates how cancer cells, particularly pancreatic ductal adenocarcinoma (PDAC), regulate oncogenic protein levels to survive, focusing on the Myc oncogene.
  • Using CRISPRi screens, four RNA binding proteins (RBPs) were identified as key activators of selective translation, with RBM42 being the most critical and linked to poor patient survival.
  • RBM42 was found to be a ribosome-associated protein that binds to the 5' untranslated region (5'UTR) of specific oncogenic transcripts, promoting their translation and supporting cancer growth, offering potential for new therapeutic strategies.
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Background: Achieving successful pain control and adequate anesthesia through an inferior alveolar nerve block for endodontic treatment in cases with symptomatic irreversible pulpitis (SIP) is difficult, especially in mandibular molars. This study was designed to compare the effect of oral medication with ibuprofen and soft laser therapy on inferior alveolar nerve block during endodontic treatment.

Methods: The trial comprised 180 patients (45 each group) with SIP.

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