Publications by authors named "S Micaletto"
Background: Specific immunotherapy for patients with honey bee hypersensitivity is commonly applied. Re-challenge with venom is performed to prove protection in individual cases.
Case Presenation: We report a case of near fatal anaphylaxis with asystole for 24 min in a 35-years-old patient with mastocytosis after honey bee sting challenge, despite 5-years of specific immunotherapy.
Article Synopsis
- Melanoma classification involves detecting oncogenic driver mutations, which influence treatment options, particularly regarding MEK inhibitors and their efficacy against NRAS-mutated melanoma.
- Two patients with NRAS-mutant metastatic melanoma showed long-term positive responses to intermittent MEK-inhibitor binimetinib therapy, suggesting that altered dosing schedules could reduce resistance to treatment.
- The article discusses the potential benefits of intermittent therapy in preventing drug resistance, alongside its toxicities and mechanisms that enhance immune system access to tumors.
Metastatic extramammary Paget's disease is a rare adenocarcinoma with poor prognosis. Several reports of human epidermal growth factor receptor 2 alterations point to its pathogenic role in the disease. However, the occurrence of treatment resistance to anti-HER2 therapy demand the need for further knowledge.
View Article and Find Full Text PDFBackground: Hymenoptera stings are a major cause of anaphylaxis. Various risk factors are discussed in literature. This study aims to investigate potential risk factors for severe sting reactions in wasp ( spp.
View Article and Find Full Text PDF