Publications by authors named "S Metso"
Aims: To assess the effect of comorbidities, risk classification for chronic kidney disease (CKD) according to albuminuria and eGFR, HbA1c and LDL-cholesterol levels on all-cause mortality in patients with type 1 diabetes (DM1).
Methods: The study included all 45,801 DM1 patients from the Finnish Diabetes Registry during 2018-2022. Mortality of patients with DM1 was compared with mortality in non-diabetic population in Finland by estimating standardized mortality rates (SMRs).
Objective: Hyperthyroidism increases cardiovascular morbidity and mortality, but the underlying mechanisms are not fully understood. In this study we compared non-invasive haemodynamics between 20 hyperthyroid patients and 60 euthyroid subjects.
Methods: The measurements were performed median 6 days after the initiation of antithyroid medication when the patients were still hyperthyroid.
Article Synopsis
- An online survey of European thyroid specialists revealed that 28% believe thyroid hormone (TH) treatment may be appropriate for euthyroid patients with growing simple goiters, despite guidelines against this practice.
- There were significant regional differences in support for TH treatment, with only 7% in The Netherlands compared to 78% in the Czech Republic.
- Factors influencing the likelihood of recommending TH included the specialist's age and the historical iodine insufficiency of their region, while gender, country, and economic factors showed weak associations.
Article Synopsis
- The study investigates the prevalence of familial hypercholesterolemia (FH) in Finnish patients with premature coronary artery disease (CAD) and high LDL cholesterol levels.
- Out of 28,295 angiography patients, 162 were identified with premature CAD, and 80 underwent genetic testing, revealing a 73% likelihood of FH among them.
- The genetically verified FH prevalence was found to be 1:16 in those with premature CAD, significantly higher than the general population rate of 1:600.
Purpose: The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as reflected in international guidelines. We explored views about this practice, and associations with respondent characteristics among European thyroid specialists.
Methods: Specialists from 28 countries were invited to a survey via professional organisations.