Vitamin D a new drug against Candida albicans.

Objective: In this study, we demonstrate that vitamin D had fungicidal activity against Candida albicans.

Material And Methods: The susceptibility of the yeast strain to the vitamin D was investigated by the antimicrobial screening using modified agar diffusion method, minimum fungistatic concentrations (MFC) and minimum fungicide concentrations (MFC) of the vitamin D were determined by the broth dilution method.

Results: The antifungal activity indicted that 100μg/ml of vitamin D had a power inhibition in the growth of C.

1-[3-(4-Nitro-phen-yl)propano-yl]urea acetic acid monosolvate.

The title compound, C(10)H(11)N(3)O(4)·C(2)H(4)O(2), was prepared by an electrochemical technique. In the crystal, acetic acid mol-ecules are involved in hydrogen bonding to two separate propano-ylurea mol-ecules, acting as a donor in an O-H⋯O inter-action and as an acceptor in two N-H⋯O inter-actions. The propano-ylurea mol-ecules inter-act with each other via N-H⋯O hydrogen bonds.