Publications by authors named "S Menting"

Introduction: Self-regulation of effort during exercise (i.e., pacing) is a determinant of exercise performance, which develops during childhood and adolescence.

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Introduction: The theory of relativity postulates that time is relative to context and exercise seems such a situation. The purpose of this study was to examine whether situational factors such as perceived exertion and the introduction of an opponent influence competitors' perception of time.

Methods: Thirty-three recreationally active adults (F = 16; M = 17) performed three standardized 4-km cycling trials in a randomized order.

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Objective: The role of intellectual disability (ID) in exercise regulation has remained largely unexplored, yet recent studies have indicated cognitive-related impaired pacing skills in people with ID. In a well-controlled laboratory environment, this study aims to (1) establish the role of ID in pacing and explore the ability of people with and without ID to maintain a steady pace; (2) to investigate if verbal feedback and/or (3) the presence of a pacer can improve the ability of people with ID to maintain a preplanned submaximal velocity.

Methods: Participants with (n=10) and without ID (n=10) were recruited and performed 7 min submaximal trials on a cycle ergometer (Velotron).

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Inappropriate prescribing of antibiotics has been widely recognised as a leading cause of antimicrobial resistance, which in turn has become one of the most significant threats to global health. Given that most antibiotic prescriptions are issued in primary care settings, investigating the associations between primary care prescribing of antibiotics and subsequent infection-related hospitalisations affords a valuable opportunity to understand the long-term health implications of primary care antibiotic intervention. A narrative review of the scientific literature studying associations between primary care antibiotic prescribing and subsequent infection-related hospitalisation was conducted.

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Article Synopsis
  • The study investigates how combining methotrexate with adalimumab treatment affects drug concentration and response in psoriasis patients.
  • A population PK-PD model was created from data collected over 49 weeks from 59 patients, revealing that methotrexate cotreatment reduces the development of antidrug antibodies, which can enhance the effectiveness of adalimumab.
  • Overall, the findings suggest that using methotrexate alongside adalimumab can lead to better treatment outcomes by increasing adalimumab levels and potentially improving clinical responses.
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