Publications by authors named "S Mendez-Flores"
Discontinuation of antiseizure medications (ASMs), primarily prompted by adverse effects, presents a formidable challenge in the management of epilepsy, and impacting up to 25% of patients. This article thoroughly explores the clinical spectrum of cutaneous adverse drug reactions (cADRs) associated with commonly prescribed ASMs. Ranging from mild maculopapular rashes to life-threatening conditions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), the diverse manifestations are meticulously detailed.
View Article and Find Full Text PDFBackground: Generalized lupus erythematosus (LEG) is an autoimmune disease with cutaneous and mucosal manifestations, with lupus cheilitis (LC) being a rare associated oral presentation. The difficulty in early diagnosis of QL lies in its various clinical forms. Although successful treatments have been described, information on specific management is limited, highlighting the importance of early recognition to improve the prognosis and quality of life of patients.
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- Anti-synthetase syndrome (AS) is a type of inflammatory muscle disease marked by specific autoantibodies and is often associated with myositis and lung issues; it sometimes includes skin lesions like those in dermatomyositis.
- A case study of a 57-year-old man revealed a rare combination of AS, deep morphea, vasculitic neuropathy, and myelodysplastic syndrome, raising questions about shared underlying mechanisms among these conditions.
- Despite receiving aggressive treatment, the patient experienced a severe decline and ultimately died from complications, underlining the complex interplay between AS and other inflammatory disorders.
A 65-year-old woman presented with unexplained weight loss, recurrent fever, and a dermatosis with painful nodules on the extremities. Biopsies showed focal lobular panniculitis with neutrophilic microgranulomas. Comprehensive investigations ruled out infection and hematologic and solid organ neoplasms.
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- Pseudolymphomatous cutaneous angiosarcoma (cAS) is a rare cancer that can be difficult to diagnose due to its similarity to other lymphoid conditions, showcasing notable lymphocyte presence.
- A unique case involving a 47-year-old woman with systemic sclerosis (SSc) is presented, characterized by facial swelling and specific imaging findings that led to a skin biopsy showing unusual vascular patterns and dense lymphocyte growth.
- This case highlights the connection between SSc and higher cancer risk, emphasizing the diagnostic challenges of cAS and the need for early detection and comprehensive management strategies.