Publications by authors named "S Melis"

Article Synopsis
  • Skeletal stem and progenitor cells (SSPCs) are essential for bone formation and repair, and they play important roles in bone diseases like osteoporosis.
  • SSPCs are found in various locations within the bone, including the periosteum and bone marrow, and can develop into several cell types, facilitating bone upkeep and blood cell production.
  • Despite significant advancements in understanding these cells, there are still unanswered questions regarding their specific functions and contributions to both healthy and diseased bone conditions, particularly as they relate to aging and metabolic disorders.
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Bone development, growth, and repair are complex processes involving various cell types and interactions, with central roles played by skeletal stem and progenitor cells. Recent research brought new insights into the skeletal precursor populations that mediate intramembranous and endochondral bone development. Later in life, many of the cellular and molecular mechanisms determining development are reactivated upon fracture, with powerful trauma-induced signaling cues triggering a variety of postnatal skeletal stem/progenitor cells (SSPCs) residing near the bone defect.

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Article Synopsis
  • Ticks, especially Ixodes ricinus, are crucial vectors for pathogens in Europe, with an expanding geographical range increasing human exposure risks.
  • A study conducted in the Lombardy region of northern Italy analyzed 350 tick samples from humans and wild animals, revealing a significant presence of various tick-borne pathogens.
  • Notably, 77% of ticks from ungulates carried Anaplasma phagocytophilum, while ticks from humans primarily harbored Borrelia burgdorferi, and multiple co-infections were also found.
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There is an increasing trend toward broiler production systems with higher welfare requirements. Breed and stocking density are considered key factors for broiler welfare that are often specified as criteria for such higher welfare systems. However, it remains unknown how slower-growing broilers respond to a reduction in stocking density with regard to their welfare and performance, and whether this response differs from fast-growing broilers.

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The use of fiber infrastructures for environmental sensing is attracting global interest, as optical fibers emerge as low cost and easily accessible platforms exhibiting a large terrestrial deployment. Moreover, optical fiber networks offer the unique advantage of providing observations of submarine areas, where the sparse existence of permanent seismic instrumentation due to cost and difficulties in deployment limits the availability of high-resolution subsea information on natural hazards in both time and space. The use of optical techniques that leverage pre-existing fiber infrastructure can efficiently provide higher resolution coverage and pave the way for the identification of the detailed structure of the Earth especially on seismogenic submarine faults.

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