Publications by authors named "S McFadden"

Introduction: Artificial intelligence (AI) is being used increasingly in image interpretation tasks. Human reliance on technology and bias can cause decision errors. A checklist, used with the AI to mitigate against such biases, may optimise the use of AI technologies and promote good decision hygiene.

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Article Synopsis
  • Aging leads to a decline in thermoregulation, lowering core body temperature (Tc), which, while being a marker of healthy aging, negatively affects cognitive function in Alzheimer's disease models.
  • The study tested whether increasing Tc through thermotherapy could enhance metabolism and cognitive performance in APP/PS1 mice by exposing them to higher temperatures (30°C) compared to standard conditions (23°C) from 6 to 12 months of age.
  • Results showed improved glucose tolerance and insulin sensitivity in mice exposed to higher temperatures, with varying effects based on sex; while male mice benefited cognitively, female APP/PS1 mice experienced worsened spatial memory, highlighting the need for more research on thermotherapy's potential
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Introduction: Feeding via a misplaced nasogastric tube (NGT) is a common but preventable cause of patient harm. The aim of this study was to determine the accuracy of diagnostic radiographers' assessment of NGT position on chest radiographs (CXRs) and safe-to-feed decisions.

Methods: A multi-case, multi-reader study was conducted using an online image interpretation platform.

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Background: It is well established that glutamatergic neurotransmission plays an essential role in learning and memory. Previous studies indicate that glutamate dynamics shift with Alzheimer's disease (AD) progression, contributing to negative cognitive outcomes.

Objective: In this study, we characterized hippocampal glutamatergic signaling with age and disease progression in a knock-in mouse model of AD (APP).

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Introduction: In Autumn 2023, amendments to the Health and Care Professions Councils (HCPC) Standards of Proficiency for Radiographers were introduced requiring clinicians to demonstrate awareness of the principles of AI and deep learning technology, and its application to practice' (HCPC 2023; standard 12.25). With the rapid deployment of AI in departments, staff must be prepared to implement and utilise AI.

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