Publications by authors named "S McCormack"
The evolution of bipedal gait is a key adaptive feature in hominids, but the running abilities of early hominins have not been extensively studied. Here, we present physics simulations of Australopithecus afarensis that demonstrate this genus was mechanically capable of bipedal running but with absolute and relative (size-normalized) maximum speeds considerably inferior to modern humans. Simulations predicted running energetics for Australopithecus that are generally consistent with values for mammals and birds of similar body size, therefore suggesting relatively low cost of transport across a limited speed range.
View Article and Find Full Text PDFBackground: Interstitial lung disease (ILD) encompasses a heterogeneous group of chronic lung conditions with considerable variability in prognosis and response to treatment. People with reduced muscle mass and function, known as sarcopenia, have a higher risk of mortality and adverse clinical outcomes both in the general population and in other chronic disease states. The importance of sarcopenia across the spectrum of patients with ILD is not well established.
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- A survey of 55 healthcare professionals in the UK explored current management practices for advanced epithelial ovarian cancer (OC), focusing on testing for homologous recombination deficiency (HRD) and BRCA mutations prior to maintenance treatment.
- All respondents emphasized the importance of considering cytoreductive surgery at first recurrence, with 65% advocating the use of DESKTOP III criteria to assist in decision-making.
- Healthcare professionals noted that most primary OC patients in the UK have established HRD and mutation status, underscoring the growing recognition of secondary cytoreduction's role in treatment.
Background: HIV self-testing (HIVST) may facilitate marginalised populations' uptake of HIV testing, but whether the extent of marginalisation challenges individual uptake of HIVST remains under-researched. We aim to explore the perspectives of multiply marginalised cis-gender gay, bisexual and other men who have sex with men (GBMSM) and trans women on whether HIVST might increase their uptake of HIV testing.
Methods: We reanalysed qualitative interview data from SELPHI (the UK's largest HIVST randomised trial) collected between 2017 and 2020 from marginalised populations, defined as people self-identifying as non-heterosexual, transgender, non-White ethnicity and/or with low educational attainment.